13 Pages, This research was conducted to assess socio-economic factors influencing adoption of conservation agriculture in Moroto District of Uganda. The socio-economic factors, the level of conservation agriculture, and the constraints faced by the farmers were assessed. A cross-sectional research design was utilised to collect data from 80 farmers (adopters and non-adopters of conservation agriculture). Purposive random sampling was applied to select seven key informants in the two sub-counties of Katikekile and Nadunget, and four villages of Nakodet, Nakwanga, Napudes and Komare. Data were collected through personal observation, interviews, focus group discussions, and structured questionnaires. The Statistical Package for Social Sciences (SPSS) was used to generate descriptive and inferential statistics for quantitative data analysis. The binary probit model was used to determine the socio-economic factors influencing adoption of conservation agriculture. The findings indicate that there was a significant influence for gender (p<0.01), but a statistically significant influence for credit and extension services (p<0.05). Finally, the adoption rate of conservation agriculture is still low given the size of land dedicated to it by most farmers. Therefore, this study recommends that government and other institutions should strengthen the agricultural extension system, provide financial support and incentives, and sensitize farmers on conservation agriculture.