9 pages, Humans have improved plants for their utility through selective self-pollination, crossing, and progeny selection for >10,000 years, largely based on physical characteristics. Less than 200 years ago, the genetic basis of heritability in selection was revealed, enabling breeders to accelerate genetic gain. Breakthroughs in genomics and molecular markers for the past century have enabled breeders to locate and select genomic regions affecting desirable traits, improving breeding precision. Transgenesis has enabled crop insertion of desirable exogenous genes, enabling de novo functionality. These technologies, along with agronomic practices, have generated more than sixfold yield improvements in crops such as corn in the past century. Gene editing, with its unique ability to precisely edit, change expression, and move genes within a crop's genome, has the potential to be the next breakthrough technology. For this to come to fruition, it is critical to take a holistic view considering perspectives of scientists, farmers, regulators, and consumers.
21 pages, Metaphors have been crucial in making genetics and genomics public, from the code and the book of life to genetic scissors and gene surgery. A new field is emerging called “gene drive” – a range of controversial technologies that can potentially be used for the eradication or conservation of animal species. At the same time, metaphors are emerging to talk about the promises and dangers of “gene drive”. In this article we use thematic analysis to examine thirty interviews with gene drive science and communication experts, and stakeholders, focusing on how they talk about their lived experience of metaphor use in the context of gene drive communication, including their struggle to remember salient metaphors and their reflections on which metaphors to use and which to avoid. We discuss the significance of our findings for research and practice of responsible science communication.
